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Don’t EVER use magnesium if you’re on any of the following medications

The claim “never use magnesium if you’re taking these medicines” is too broad. Magnesium is an essential mineral, and many people can take a magnesium supplement safely. The important issues are which medication you’re taking, the dose, timing, and your kidney function.

Medicines that can interact with magnesium

  • Certain antibiotics — magnesium can bind to drugs such as doxycycline, ciprofloxacin and levofloxacin, reducing their absorption. They usually need to be taken several hours apart.
  • Bisphosphonates such as alendronate — magnesium can reduce absorption, so the medicines should be separated.
  • Diuretics (“water pills”) — furosemide and hydrochlorothiazide can alter magnesium levels, while some other diuretics have different effects.
  • Digoxin — electrolyte changes can affect the safety of this heart medicine, so don’t add magnesium without discussing it with your doctor/pharmacist.
  • Some acid-reducing medicines — long-term proton-pump inhibitors can lower magnesium levels and may require monitoring.

⚠️ The biggest concern: kidney disease

If your kidneys aren’t working properly, they may not remove magnesium efficiently. High magnesium levels can cause low blood pressure, weakness, confusion, breathing problems and abnormal heart rhythms.

Also remember that magnesium can be present in antacids and laxatives, not just supplements.

Don’t stop a prescribed medicine because of this headline. And don’t start high-dose magnesium without checking your medications and kidney function.

If you give me the names and doses of the medicines you take and the magnesium product/dose, I can tell you specifically which combinations are a concern and whether they need to be separated.

 

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